Epidemiology of Hyperbilirubinemia in a Quaternary Pediatric Emergency Department over a Three-Year Period / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition
;
: 297-305, 2018.
Article
in English
| WPRIM
| ID: wpr-717807
ABSTRACT
PURPOSE:
There is a lack of scholarly reports on pediatric emergency department (PED) exposure to hyperbilirubinemia. We aimed to describe the epidemiology of hyperbilirubinemia in patients presenting to a PED over a three-year period.METHODS:
This was a retrospective cohort study, completed at an urban quaternary academic PED. Patients were included if they presented to the PED from 2010 to 2012, were 0 to 18 years in age, and had an elevated serum bilirubin for age. A chart review was completed to determine the incidence of hyperbilirubinemia, etiology, diagnostic work up and prognosis. The data set was stratified into four age ranges.RESULTS:
We identified 1,534 visits where a patient was found to have hyperbilirubinemia (0.8% of all visits). In 47.7% of patients hyperbilirubinemia was determined to have arisen from an identifiable pathologic etiology (0.38% of all visits). First-time diagnosis of pathologic hyperbilirubinemia occurred in 14% of hyperbilirubinemia visits (0.11% of all visits). There were varying etiologies of hyperbilirubinemia across age groups but a male predominance in all (55.0%). 15 patients went on to have a liver transplant and 20 patients died. First-time pathologic hyperbilirubinemia patients had a mortality rate of 0.95% for their initial hospitalization.CONCLUSION:
Hyperbilirubinemia was not a common presentation to the PED and a minority of cases were pathologic in etiology. The etiologies of hyperbilirubinemia varied across each of our study age groups. A new discovery of pathologic hyperbilirubinemia and progression to liver transplant or death during the initial presentation was extremely rare.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pediatrics
/
Prognosis
/
Bilirubin
/
Epidemiology
/
Incidence
/
Retrospective Studies
/
Cohort Studies
/
Mortality
/
Diagnosis
/
Emergencies
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Humans
/
Male
Language:
English
Journal:
Pediatric Gastroenterology, Hepatology & Nutrition
Year:
2018
Type:
Article
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