For Better Fat Graft Outcome in Soft Tissue Augmentation: Systematic Review and Meta-Analysis
Archives of Aesthetic Plastic Surgery
;
: 116-127, 2018.
Article
in English
| WPRIM
| ID: wpr-717924
ABSTRACT
BACKGROUND:
Autologous fat grafts are widely used in plastic surgery, but they have the disadvantage of unpredictability due to variable resorption. This meta-analysis examined the literature on the survival rate of autologous fat grafts using objective markers, and investigated the factors that affected the survival rate.METHODS:
The reviewers searched the PubMed, EMBASE, and Cochrane Library databases from January 2001 to December 2017. A meta-analysis was performed to estimate fat graft survival and to identify variables that influenced the survival rate.RESULTS:
A total of 27 studies (1,066 cases) were included in the meta-analysis. The mean survival rate of grafted fat was 56.5%. The survival rate was significantly higher for cell-assisted lipotransfer (CAL) than for non-CAL (62% vs. 53.4%; P=0.015). The survival rate for procedures performed to correct lipoatrophy was higher than that of procedures performed for other purposes (64.6%; P=0.014), and was significantly higher in patients who underwent breast pre-expansion using the BRAVA device (66.2% vs. 50.35%; P=0.001). There were no significant differences in the survival rate according to the recipient site, harvesting method, or refinement method.CONCLUSIONS:
Fat transplantation showed a varying survival rate, with an average of 56%. In patients who underwent CAL or breast pre-expansion with the BRAVA device, the survival rate of transplanted fat was higher than in their counterparts, supporting the use of these techniques in fat transplantation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Surgery, Plastic
/
Breast
/
Survival Rate
/
Analysis of Variance
/
Transplants
/
Adult Stem Cells
/
Autografts
/
Graft Survival
/
Methods
Type of study:
Prognostic study
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Archives of Aesthetic Plastic Surgery
Year:
2018
Type:
Article
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