Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions
Clinical Endoscopy
;
: 576-583, 2018.
Article
in English
| WPRIM
| ID: wpr-717969
ABSTRACT
BACKGROUND/AIMS:
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique.METHODS:
Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis.RESULTS:
Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p < 0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain.CONCLUSIONS:
The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Abdominal Pain
/
Prospective Studies
/
Biopsy, Fine-Needle
/
Diagnosis
/
Endoscopic Ultrasound-Guided Fine Needle Aspiration
/
Needles
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
English
Journal:
Clinical Endoscopy
Year:
2018
Type:
Article
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