Promotion of excisional wound repair by a menstrual blood-derived stem cell-seeded decellularized human amniotic membrane
Biomedical Engineering Letters
;
(4): 393-398, 2018.
Article
in English
| WPRIM
| ID: wpr-717984
ABSTRACT
This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via decellularized human amniotic membrane (DAM), for the promotion of skin excisional wound repair. The DAM was seeded with MenSCs at the density of 3 × 10⁴ cells/cm² and implanted onto a rat's 1.50 × 1.50 cm² full-thickness excisional wound defect. The results of wound closure and histopathological examinations demonstrated that the MenSC-seeded DAM could significantly improve the wound healing compared with DAM-treatment. All in all, our data indicated that the MenSCs can be a potential source for cell-based therapies to regenerate skin injuries.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Stem Cells
/
Wound Healing
/
Wounds and Injuries
/
Amnion
Limits:
Humans
Language:
English
Journal:
Biomedical Engineering Letters
Year:
2018
Type:
Article
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