Kidney transplantation using expanded criteria deceased donors with terminal acute kidney injury: a single center experience in Korea
Annals of Surgical Treatment and Research
;
: 278-285, 2018.
Article
in English
| WPRIM
| ID: wpr-718337
ABSTRACT
PURPOSE:
We investigated the clinical outcomes of deceased donor kidney transplantation (KT) using kidneys with terminal acute kidney injury (AKI).METHODS:
Between February 2000 and December 2013, we performed 202 deceased donor renal transplants from 159 brain dead donors. According to the expanded criteria donor (ECD) and AKI network criteria, we divided 202 recipients into 4 groups Group I Non-AKI & standard criteria donor (SCD) (n = 97); group II Non-AKI & ECD (n = 15); group III AKI & SCD (n = 52); and group IV AKI & ECD (n = 38).RESULTS:
The incidence of delayed graft function (DFG) was significantly higher in patients with AKI than it was in the non-AKI group (P = 0.008). There were no significant differences among the 4 groups in graft survival (P = 0.074) or patient survival (P = 0.090). However, the long-term allograft survival rate was significantly lower in group IV than it was in other groups (P = 0.024).CONCLUSION:
Allografts from deceased donors with terminal AKI had a higher incidence of DGF than did those from donors without AKI. However, there is no significant difference in graft and patient survival rates among the groups. So, the utilization of renal grafts from ECDs with terminal AKI is a feasible approach to address the critical organ shortage.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Brain Death
/
Incidence
/
Survival Rate
/
Kidney Transplantation
/
Transplants
/
Delayed Graft Function
/
Acute Kidney Injury
/
Allografts
/
Graft Survival
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2018
Type:
Article
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