Acute combined central and peripheral nervous system demyelination: a case report / 고신대학교의과대학학술지
Kosin Medical Journal
;
: 257-262, 2018.
Article
in English
| WPRIM
| ID: wpr-718457
ABSTRACT
Guillain-Barré syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) are demyelinating neurologic disorders with different target organs. Although they share similar pathogenetic mechanism, reports of simultaneous occurrence of the 2 disorders are rare. A 2 year 6 month old girl visited our hospital for fever, cough, and general weakness. Although the muscle power of extremities showed mild weakness and voiding difficulty, initial deep tendon reflex of both knees and ankles was normal. A nerve conduction study to evaluate the weakness revealed the absence of F waves. Cerebrospinal fluid analysis demonstrated pleocytosis with lymphocyte predominance and elevated protein levels. Magnetic resonance imaging showed abnormal T2 hyperintensity in pons, medulla and spinal cord. Serum anti-GD1b antibody was positive. Based on clinical findings, laboratory findings, nerve conduction study, and neuroimaging, the diagnosis of GBS and ADEM was made. This is the first case of GBS accompanied by ADEM in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reflex, Stretch
/
Spinal Cord
/
Pons
/
Magnetic Resonance Imaging
/
Lymphocytes
/
Cerebrospinal Fluid
/
Demyelinating Diseases
/
Peripheral Nervous System
/
Cough
/
Guillain-Barre Syndrome
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Kosin Medical Journal
Year:
2018
Type:
Article
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