Comparison of Clinical Characteristics and Severity of Glyphosate and Glufosinate Herbicide Poisoning Patients
Journal of The Korean Society of Clinical Toxicology
;
: 124-130, 2018.
Article
in Korean
| WPRIM
| ID: wpr-718678
ABSTRACT
PURPOSE:
The number of glyphosate and glufosinate intoxication cases are increasing in Korea. This study was undertaken is to compare the clinical manifestations of poisoning by these two herbicides and to document severities and clinical outcomes.METHODS:
We retrospectively evaluated cases of glyphosate or glufosinate intoxication among patients that visited our emergency department between January 1, 2013, and December 31, 2017. Incidences of intoxications were analyzed over this five year period, and underlying diseases, transportation, mental state, shock occurrence, inotropics, gastric lavage, charcoal administration, intubation and ventilator therapy, and hemodialysis were investigated. In addition, we included transfer to the intensive care unit, incidences of pneumonia and of other complications, death, and hopeless discharge.RESULTS:
There were 119 cases of glyphosate intoxication and 42 of glufosinate intoxication. Levels of consciousness were lower for glufosinate and vasopressor usage was higher due to a high shock rate (p=0.019). In addition, many patients were referred to the ICU for intubation and ventilation. The incidences of pneumonia and of other complications were significantly higher for glufosinate.CONCLUSION:
Overall glufosinate intoxication was found to be more severe than glyphosate intoxication as determined by complication and ICU admission rates.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Poisoning
/
Shock
/
Transportation
/
Ventilation
/
Ventilators, Mechanical
/
Charcoal
/
Incidence
/
Retrospective Studies
/
Renal Dialysis
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of The Korean Society of Clinical Toxicology
Year:
2018
Type:
Article
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