Recurrent Clostridium difficile Infection: Risk Factors, Treatment, and Prevention
Gut and Liver
;
: 16-24, 2019.
Article
in English
| WPRIM
| ID: wpr-719258
ABSTRACT
The most common cause of antibiotic-associated diarrhea is Clostridium difficile infection (CDI). Recurrent C. difficile infection (rCDI) often occurs after successful treatment of CDI. Due to the increased incidence and the difficulty in treating rCDI, it is becoming an important clinical issue. Identifying risk factors is helpful for early detection, treatment, and prevention of rCDI. Advanced age, use of antibiotics, gastric acid suppression, and infection with a hypervirulent strain are currently regarded as the major risk factors for rCDI. Several treatment modalities, including vancomycin, fidaxomicin, and fecal microbiota transplant (FMT), are suggested for rCDI treatment. However, there is currently no definitive treatment method with sufficient evidence for rCDI. Recent studies have focused on FMT and have shown positive results for rCDI. Prevention of rCDI by measures such as hand washing and isolation of patients is very important. However, these preventive measures are often overlooked in clinical practice. Here, we review the risk factors, treatment, and prevention of rCDI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Vancomycin
/
Hand Disinfection
/
Incidence
/
Risk Factors
/
Clostridioides difficile
/
Clostridium
/
Diarrhea
/
Microbiota
/
Gastric Acid
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Humans
Language:
English
Journal:
Gut and Liver
Year:
2019
Type:
Article
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