A Case of Acute Panmyelosis with Myelofibrosis / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 207-211, 2004.
Article
in Korean
| WPRIM
| ID: wpr-71945
ABSTRACT
We experienced a case of acute panmyelosis with myelofibrosis, one of the acute myeloblastic leukemia (AML) subtypes according to WHO classification. A 44 year old man presented with a laborious dyspnea, dizziness, and generalized weakness. On admission, the peripheral blood revealed pancytopenia (hemoglobin 4.0 g/dL, WBC 2, 300/microliter, platelet 92, 000/microliter) with leukoerythroblastosis. The bone marrow (BM) aspirate yielded inadequate material but histological sections showed hyper-cellularity, proliferation of trilineage cell lines (panmyelosis) with extensive myelofibrosis, and clusters of immature cells at paratrabecular area. On ultrasonographic examination, no evidence of hepato-splenomegaly or any other abnormalities were noted. The follow-up BM study after the chemotherapy with Ara C for 7 days and idarubicin for 3 days showed no significant changes in pancytopenia and myelofibrosis but revealed a significant decrease in BM cellularity and blasts. We review and report the literature on acute panmyelosis with myelofibrosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancytopenia
/
Blood Platelets
/
Bone Marrow
/
Idarubicin
/
Leukemia, Myeloid, Acute
/
Cell Line
/
Follow-Up Studies
/
Classification
/
Dizziness
/
Drug Therapy
Type of study:
Observational study
/
Prognostic study
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2004
Type:
Article
Similar
MEDLINE
...
LILACS
LIS