Choroidal Thickness Analysis in Patients with Erectile Dysfunction
The World Journal of Men's Health
;
: 85-92, 2019.
Article
in English
| WPRIM
| ID: wpr-719627
ABSTRACT
PURPOSE:
To investigate the morphological features of choroidal vasculature in patients with erectile dysfunction (ED) by analyzing choroidal thickness using optical coherence tomography. MATERIALS ANDMETHODS:
We enrolled 39 patients with ED and 19 controls. ED was defined as an erectile function domain score < 26 on the International Index of Erectile Function (IIEF) questionnaire. Small-choroidal-vessel-layer (SCVL) thickness was calculated by subtracting large-choroidal-vessel-layer (which corresponded to Haller's layer) thickness from total choroidal thickness. Choroidal thickness was compared between the ED and control groups.RESULTS:
SCVL thickness was lesser in the ED group than in the control group (control, 69.8±24.3 µm vs. ED, 55.1±19.9 µm; p=0.017). Among patients without diabetes, the ED group showed significantly lesser SCVL thickness than did the control group (control, 77.1±22.7 µm vs. ED, 56.5±20.9 µm; p=0.021). However, among patients with diabetes, choroidal thickness showed no significant intergroup difference. Multiple linear regression analysis revealed that spherical equivalent (standardized coefficient β=0.294; p=0.019) and the IIEF erectile function score (standardized coefficient β=0.315; p=0.012) were significantly associated with SCVL thickness.CONCLUSIONS:
SCVL thickness, including the choriocapillaris layer and medium-sized choroidal vascular layer, decreased in proportion to ED severity, suggesting that microvascular changes in choroidal vessels may occur before specific ocular diseases in patients with ED.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Linear Models
/
Choroid
/
Tomography, Optical Coherence
/
Erectile Dysfunction
Type of study:
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
The World Journal of Men's Health
Year:
2019
Type:
Article
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