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Testicular Fine-Needle Aspiration for Sperm Retrieval in Azoospermia: A Small Step toward the Technical Standardization
The World Journal of Men's Health ; : 55-67, 2019.
Article in English | WPRIM | ID: wpr-719630
ABSTRACT

PURPOSE:

The aim was to describe our preliminary experience performing testicular fine-needle aspiration (TEFNA) with a larger needle in infertile patients with obstructive azoospermia, and to provide a systematic literature review of the different testicular sperm aspiration techniques, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. MATERIALS AND

METHODS:

We prospectively collected data between March 2017 and June 2018. All men underwent bilateral TEFNA under analgo-sedation, using a larger disposable 18-gauge butterfly needle with 60 mL Luer-Lock syringe attached to it.

RESULTS:

Thirty consecutive patients were enrolled. Median operative time was 16 minutes (interquartile range [IQR] 12–30 minutes). No intraoperative complications occurred. Two/thirty patients (6.7%) reported postoperative adverse events 1 patient had prolonged orchialgia, 1 patient presented scrotal hematoma. Successful sperm retrieval was found in 28/30 cases (93.3%). Median sperm concentration was 0.05 ×106/mL (IQR 0.001–0.1 ×106/mL). Median total sperm motility was 10% (IQR 0%–15%). In 20/30 men (66.7%) sperm retrieved was used for fresh intracytoplasmic sperm injection cycle, in 8/30 (26.7%) sperm cryopreservation was necessary, because on the day of sperm retrieval the female resulted not responder to ovarian stimulation. In this cases mean number of 3 (IQR 1–4) bio system straws was cryopreserved.

CONCLUSIONS:

TEFNA with 18-gauge needle proved to be a feasible, safe and effective treatment, even if future prospective studies will be addressed to clarify what type of azoospermia benefits from this procedure, and if a larger needle permits to improve Assisted Reproductive Technologies (ART) outcomes.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Ovulation Induction / Sperm Motility / Spermatozoa / Syringes / Butterflies / Cryopreservation / Prospective Studies / Reproductive Techniques / Sperm Injections, Intracytoplasmic / Reproductive Techniques, Assisted Type of study: Practice guideline / Observational study Limits: Female / Humans / Male Language: English Journal: The World Journal of Men's Health Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Ovulation Induction / Sperm Motility / Spermatozoa / Syringes / Butterflies / Cryopreservation / Prospective Studies / Reproductive Techniques / Sperm Injections, Intracytoplasmic / Reproductive Techniques, Assisted Type of study: Practice guideline / Observational study Limits: Female / Humans / Male Language: English Journal: The World Journal of Men's Health Year: 2019 Type: Article