Cross-Sectional Relations of Arterial Stiffness and Inflammatory Markers in Korean Adults Aged 50 Years and Older / 農村醫學 地域保健
Journal of Agricultural Medicine & Community Health
;
: 101-112, 2011.
Article
in Korean
| WPRIM
| ID: wpr-719997
ABSTRACT
OBJECTIVES:
The aim of this study is to determine arterial stiffness levels as measured by brachial-ankle pulse wave velocity (baPWV) and to identify the association between arterial stiffness and inflammatory markers, in healthy adults over 50 years old.METHODS:
The study population consisted of 4617 persons over the age of 50 years who participated in the baseline survey of the Dong-gu Study, which was conducted in 2007 and 2008. Arterial stiffness was measured using baPWV. A multiple regression analysis was performed to assess the relationship between conventional cardiovascular risk factors and inflammatory markers, including white blood cell (WBC) counts, high-sensitive C-reactive protein (hs-CRP), and gamma glutamyltransferase (GGT).RESULTS:
After adjustment for conventional cardiovascular risk factors including sex, age, smoking status, body mass index, systolic blood pressure, fasting glucose, hypertension or diabetic medication, total cholesterol, triglycerides, uric acid, and alanine aminotransferase, baPWV was significantly associated with WBC counts (beta=0.158, p<0.0001), hs-CRP (beta=0.244, p=0.026), and GGT (beta=0.003, p<0.0001).CONCLUSION:
This study shows that arterial stiffness correlates with inflammatory markers. Arterial stiffness may be used as a composite risk factor to identify persons with higher risk for cardiovascular disease. Additionally, arterial stiffness may be a marker for future cardiovascular disease and a target for prevention.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Triglycerides
/
Uric Acid
/
Blood Pressure
/
C-Reactive Protein
/
Cardiovascular Diseases
/
Smoking
/
Body Mass Index
/
Cholesterol
/
Surveys and Questionnaires
Type of study:
Etiology study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Humans
Language:
Korean
Journal:
Journal of Agricultural Medicine & Community Health
Year:
2011
Type:
Article
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