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A Case of Successful Allogeneic Stem Cell Transplantation for Chemotherapy-refractory Hepatosplenic gamma delta-T Cell Lymphoma / 대한혈액학회지
Korean Journal of Hematology ; : 284-288, 2009.
Article in Korean | WPRIM | ID: wpr-720071
ABSTRACT
Hepatosplenic T-cell lymphoma is a rare histologic type of peripheral T-cell lymphoma, which is characterized clinically by predominant involvement of the liver and spleen, with little or no adenopathy, and an often aggressive course. We experienced a case of a 44-year-old female who was diagnosed with hepatosplenic gamma delta T-cell lymphoma with bone marrow involvement. The patient was treated with multi- agent chemotherapy with Bortezomib plus CHOP (cyclophosphamide, vincristine, prednisone, doxorubicin), Alemtuzumab plus DHAP (dexamethasone, cisplatin, cytarabine), and IMVP-16 (Ifosfamide, MTX, etoposide); however, she failed to achieve partial remission. After salvage chemotherapy (GemOx Gembicine, oxaliplatin, dexamethasone), she underwent allogeneic stem cell transplantation from an HLA sibling donor with one mismatch . The patient is currently living and has remained in complete remission for 6 months since transplantation.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Organoplatinum Compounds / Pyrazines / Spleen / Stem Cells / Tissue Donors / Vincristine / Bone Marrow / Boronic Acids / Prednisone / Lymphoma, T-Cell Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Hematology Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Organoplatinum Compounds / Pyrazines / Spleen / Stem Cells / Tissue Donors / Vincristine / Bone Marrow / Boronic Acids / Prednisone / Lymphoma, T-Cell Limits: Adult / Female / Humans Language: Korean Journal: Korean Journal of Hematology Year: 2009 Type: Article