Splenic infarction in a patient with autoimmune hemolytic anemia and protein C deficiency / 대한혈액학회지
Korean Journal of Hematology
;
: 274-278, 2011.
Article
in English
| WPRIM
| ID: wpr-720153
ABSTRACT
Splenic infarction is most commonly caused by cardiovascular thromboembolism; however, splenic infarction can also occur in hematologic diseases, including sickle cell disease, hereditary spherocytosis, chronic myeloproliferative disease, leukemia, and lymphoma. Although 10% of splenic infarction is caused by hematologic diseases, it seldom accompanies autoimmune hemolytic anemia (AIHA). We report a case of a 47-year-old woman with iron deficiency anemia who presented with pain in the left upper abdominal quadrant, and was diagnosed with AIHA and splenic infarction. Protein C activity and antigen decreased to 44.0% (60-140%) and 42.0% (65-140%), respectively. Laboratory testing confirmed no clinical cause for protein C deficiency, such as disseminated intravascular coagulation, sepsis, hepatic dysfunction, or acute respiratory distress syndrome. Protein C deficiency with splenic infarction has been reported in patients with viral infection, hereditary spherocytosis, and leukemia. This is a rare case of splenic infarction and transient protein C deficiency in a patient with AIHA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Respiratory Distress Syndrome
/
Spherocytosis, Hereditary
/
Splenic Infarction
/
Protein C
/
Leukemia
/
Sepsis
/
Anemia, Iron-Deficiency
/
Protein C Deficiency
/
Disseminated Intravascular Coagulation
/
Hematologic Diseases
Limits:
Female
/
Humans
Language:
English
Journal:
Korean Journal of Hematology
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS