CD56+ T-cell Prolymphocytic Leukemia Showing a High Expression Level of TCL1 Oncogene: A Case Report with a Review of the Literature / 대한혈액학회지
Korean Journal of Hematology
;
: 129-133, 2006.
Article
in Korean
| WPRIM
| ID: wpr-720230
ABSTRACT
T-cell prolymphocytic leukemia (T-PLL) is a rare mature post-thymic T-cell malignancy with infiltration to the blood, bone marrow, lymph node, liver, spleen and skin; this disease has a poor prognosis and an aggressive clinical course. We report here on a case of CD56+ T-PLL that was diagnosed by hematological examination, immunophenotyping and molecular studies including determining the TCL1 expression by using reverse-transcriptase polymerase chain reaction (RT-PCR), and direct sequencing of the RT-PCR product.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oncogenes
/
Prognosis
/
Skin
/
Spleen
/
Bone Marrow
/
T-Lymphocytes
/
Leukemia, Prolymphocytic, T-Cell
/
Polymerase Chain Reaction
/
Immunophenotyping
/
Liver
Type of study:
Prognostic study
Language:
Korean
Journal:
Korean Journal of Hematology
Year:
2006
Type:
Article
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