Complete Hematologic Response and Cytogenetic Remission after Imatinib and Dexamethasone Treatment of a Ph+ Precursor B-cell Acute Lymphoblastic Leukemia in Renal Transplantation Patient / 대한혈액학회지
Korean Journal of Hematology
;
: 62-66, 2009.
Article
in English
| WPRIM
| ID: wpr-720426
ABSTRACT
In this report, we present a case of a patient with Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia after renal transplantation. The patient, a 65-year-old man, had received a kidney transplantation 20 years prior to diagnosis with Ph+ precursor B-cell ALL. Because he was refractory to intensive chemotherapy and had refused to receive additional intensive chemotherapy, he was treated with imatinib and dexamethasone. While this patient experienced a complete hematologic and cytogenetic response, he did not show a complete molecular remission. Eighty days after imatinib combination therapy, the patient relapsed and died from intracerebral hemorrhage.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Piperazines
/
Pyrimidines
/
Benzamides
/
Philadelphia Chromosome
/
Dexamethasone
/
B-Lymphocytes
/
Cerebral Hemorrhage
/
Philadelphia
/
Kidney Transplantation
/
Cytogenetics
Limits:
Aged
/
Humans
Country/Region as subject:
North America
Language:
English
Journal:
Korean Journal of Hematology
Year:
2009
Type:
Article
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