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Complete Hematologic Response and Cytogenetic Remission after Imatinib and Dexamethasone Treatment of a Ph+ Precursor B-cell Acute Lymphoblastic Leukemia in Renal Transplantation Patient / 대한혈액학회지
Korean Journal of Hematology ; : 62-66, 2009.
Article in English | WPRIM | ID: wpr-720426
ABSTRACT
In this report, we present a case of a patient with Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia after renal transplantation. The patient, a 65-year-old man, had received a kidney transplantation 20 years prior to diagnosis with Ph+ precursor B-cell ALL. Because he was refractory to intensive chemotherapy and had refused to receive additional intensive chemotherapy, he was treated with imatinib and dexamethasone. While this patient experienced a complete hematologic and cytogenetic response, he did not show a complete molecular remission. Eighty days after imatinib combination therapy, the patient relapsed and died from intracerebral hemorrhage.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Piperazines / Pyrimidines / Benzamides / Philadelphia Chromosome / Dexamethasone / B-Lymphocytes / Cerebral Hemorrhage / Philadelphia / Kidney Transplantation / Cytogenetics Limits: Aged / Humans Country/Region as subject: North America Language: English Journal: Korean Journal of Hematology Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Piperazines / Pyrimidines / Benzamides / Philadelphia Chromosome / Dexamethasone / B-Lymphocytes / Cerebral Hemorrhage / Philadelphia / Kidney Transplantation / Cytogenetics Limits: Aged / Humans Country/Region as subject: North America Language: English Journal: Korean Journal of Hematology Year: 2009 Type: Article