Metachronous Mantle Cell Lymphoma with Leukemic Presentation in a Patient with Early Gastric Cancer: A Case Report / 대한혈액학회지
Korean Journal of Hematology
;
: 247-252, 2008.
Article
in English
| WPRIM
| ID: wpr-720503
ABSTRACT
We report here on a case of metachronous second primary non-Hodgkin's lymphoma (NHL) that was diagnosed 6 years after performing subtotal gastrectomy for treating early gastric cancer (EGC). The subtype analysis revealed mantle cell lymphoma (MCL) of the blastic variant with a leukemic presentation, which was composed of mixed small and medium-sized cells. The immunohistochemical staining for cyclin-D1 was positive. The cytogenetic study revealed t(4;6). In Korea, the risk of developing a second primary cancer following gastric cancer was reported to be less than 3.4%, and NHL comprised less than 6.3% of this second primary cancer. Furthermore, MCL represents about 2% of all lymphomas in Korea. To the best of our knowledge, this is the first report of metachronous primary MCL with a leukemic presentation following curative resection of EGC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Lymphoma, Non-Hodgkin
/
Leukemia
/
Neoplasms, Second Primary
/
Lymphoma, Mantle-Cell
/
Cytogenetics
/
Gastrectomy
/
Korea
/
Lymphoma
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Hematology
Year:
2008
Type:
Article
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