Long-term disease-free survival of patients with primary cardiac lymphoma treated with systemic chemotherapy and radiotherapy
Korean Journal of Hematology
; : 282-285, 2010.
Article
in En
| WPRIM
| ID: wpr-720651
Responsible library:
WPRO
ABSTRACT
Primary cardiac lymphoma (PCL) is a rare disease entity with only a few reported cases in Korea. In this paper, we report a case of PCL in a 59-year-old man presenting with chest pain. Diffuse large B-cell lymphoma was diagnosed through a cardiac catheterization-assisted percutaneous endomyocardial biopsy, and there was no evidence of extracardiac involvement of the lymphoma.The patient had a complete clinical response after systemic chemotherapy with a rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) regimen and additional post-chemotherapeutic radiation therapy. The patient experienced a long-term disease-free survival of over 4 years. However, he received coronary artery bypass graft surgery due to an acute myocardial infarction that occurred 3 years after the completion of the radiation therapy. Although the addition of radiation therapy to the treatment is thought to decrease the risk of relapse in patients with PCL, a careful and thorough consideration of the potential complications of radiation therapy, particularly with respect to cardiac complications, should be considered.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Recurrence
/
Vincristine
/
Biopsy
/
Chest Pain
/
Prednisolone
/
Doxorubicin
/
Coronary Artery Bypass
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Lymphoma, B-Cell
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Disease-Free Survival
/
Transplants
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Korean Journal of Hematology
Year:
2010
Type:
Article