A Case of Invasive Pulmonary Aspergillosis Cured with Liposomal Amphotericin, Granulocyte Transfusion and Surgery in an Allogeneic Hemopoietic Stem Cell Transplantation Recipient / 대한혈액학회지
Korean Journal of Hematology
;
: 625-629, 1999.
Article
in Korean
| WPRIM
| ID: wpr-720669
ABSTRACT
The prognosis of invasive aspergillosis in allogeneic bone marrow transplantation recipients is grave in the absence of bone marrow recovery in spite of antifungal treatment with amphotericin B. Beneficial role of granulocyte transfusion in neutropenic patients with fungal infection has been re-evaluated since granulocyte colony-stimulating factor made effective collection of granulocyte possible. And Liposomal amphotericin appears to be an effective alternative to conventional amphotericin B with much less toxicity. A 34-year-old patient with acute lymphoblastic leukemia developed invasive pulmonary aspergillosis during very early period of allogeneic hemopoietic stem cell transplantation. We treated the case successfully with liposomal amphotericin and granulocyte transfusion and surgery in spite of known high mortality of invasive aspergillosis in transplantation patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Aspergillosis
/
Stem Cells
/
Bone Marrow
/
Leukemia
/
Amphotericin B
/
Mortality
/
Granulocyte Colony-Stimulating Factor
/
Bone Marrow Transplantation
/
Stem Cell Transplantation
Type of study:
Prognostic study
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Hematology
Year:
1999
Type:
Article
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