A Case of Hyperammonemic Encephalopathy with Serum Amino Acid Alteration in Multiple Myeloma / 대한혈액학회지
Korean Journal of Hematology
;
: 64-67, 2003.
Article
in Korean
| WPRIM
| ID: wpr-720949
ABSTRACT
Disturbance of consciousness in patients with multiple myeloma is usually related with uremia, hypercalcemia or hyperviscosity syndrome. Currently, hyperammonemic encephalopathy which accompanies characteristic change of amino acid levels in pheripheral blood has been reported as a rare cause of mental change in multiple myeloma. We experienced a case of hyperammonemic encephalopathy in a 60-year-old man with multiple myeloma who had shown transient response to the combination chemotherapy with melphalan and prednisolone. Measurement of amino acid concentrations in peripheral blood revealed high glycine/tyrosine ratio and low Fisher ratio. In spite of conventional treatment on hyperammonemic encephalopathy, he died of disease progression without improvement of consciousness level.
Full text:
Available
Index:
WPRIM (Western Pacific)
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Hematology
Year:
2003
Type:
Article
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