Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1692-1695, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-721073
ABSTRACT
@#AIM:
To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p>METHODS:
Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p>RESULTS:
Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i>P</i><0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup>2</sup> to 53.81±20.41nV/deg<sup>2</sup>(<i>P</i>=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i>r</i>=-0.776, <i>P</i><0.001). <p>CONCLUSION:
Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
International Eye Science
Year:
2018
Type:
Article
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