Green Tea Consumption and Stomach Cancer Risk: A Meta-Analysis / 한국역학회지
Epidemiology and Health
;
: e2010001-2010.
Article
in English
| WPRIM
| ID: wpr-721314
ABSTRACT
OBJECTIVES:
Green tea has been suggested to have a chemopreventive effect against various cancers including stomach cancer. The aim of this study is to elucidate the relationship between green tea consumption and stomach cancer risk by meta-analysis.METHODS:
Eighteen observational studies were identified using MEDLINE, THE COCHRANE LIBRARY, RISS, and a manual search. Summary relative risks/odds ratios (RR/ORs) for the highest versus non/lowest green tea consumption levels were calculated on the basis of fixed and random effect models. Subgroup analyses were used to examine heterogeneity across the studies.RESULTS:
The combined results indicate a reduced risk of stomach cancer with intake of green tea (RR/OR=0.86, 95% CI=0.74-1.00). Subgroup analysis with six studies that reported differences between the highest and lowest consumption levels equal to or greater than five cups/day revealed a statistically significant protective effect (RR/OR=0.68, 95% CI=0.53-0.87).CONCLUSION:
Green tea appears to play a protective role against the development of stomach cancer. The results also suggest that a higher level of green tea consumption might be needed for a clear preventive effect to appear. This conclusion, however, should be interpreted with caution because various biases can affect the results of a meta-analysis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Stomach Neoplasms
/
Tea
/
Population Characteristics
/
Bias
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Systematic reviews
Language:
English
Journal:
Epidemiology and Health
Year:
2010
Type:
Article
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