Analysis on the Etiology and Prognostic Factors of Community-Acquired Bacteremia in a Community-Based Tertiary Hospital / 감염과화학요법
Infection and Chemotherapy
;
: 255-264, 2005.
Article
in Korean
| WPRIM
| ID: wpr-721438
ABSTRACT
BACKGROUND:
We conducted this study to describe the epidemiology of community-acquired bacteremia and identify its prognostic factors. MATERIALS ANDMETHODS:
All patients admitted to a community-based tertiary hospital with community-acquired bacteremia from June 2002 to May 2004 were included and analyzed retrospectively.RESULTS:
During the study period, clinically significant community-acquired bacteremia occurred in 223 patients with the frequency of 5.3 patients per 1,000 patient-admission. The commonly isolated organisms were E. coli (47.1%), K. pneumoniae (13.0%), S. aureus (8.1%), and S. pneumoniae (4.5 %). The leading source of bacteremia were urinary tract infection (34.5%), intraabdominal infection (33.6%), primary bacteremia (10.3%), and skin & soft tissue infection (8.1%). The overall mortality was 17%. S. aureus (34.8%) and K. pneumoniae (30.4%) were two major organisms of primary bacteremia with high case fatality of 50% and 28.6%, respectively. Univariate analysis showed that the followings were associated with significant increase in mortality male patient; S. aureus and other streptococci bacteremia; increasing APACHE II score; definite diagnosis after 3 days of admission; inappropriate antibiotics therapy within 24 hours of admission; emergency room; admission to ICU. The independent predictors of mortality were male patient (RR 3.02, P=0.031), increasing APACHE II score (RR 1.12, P=0.011), and admission to ICU (RR 9.73, P<0.001).CONCLUSION:
Rapid definite diagnosis and prompt administration of appropriate antibiotics according to the local epidemiologic pattern are the most important controllable factors for the better outcome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Prognosis
/
Skin
/
Urinary Tract Infections
/
Epidemiology
/
Retrospective Studies
/
Mortality
/
Bacteremia
/
Soft Tissue Infections
/
APACHE
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2005
Type:
Article
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