Causative Organisms and Antimicrobial Susceptibility of Urinary Tract Infection of Spinal Cord Injured Patients / 감염과화학요법
Infection and Chemotherapy
;
: 243-247, 2007.
Article
in Korean
| WPRIM
| ID: wpr-721506
ABSTRACT
BACKGROUND:
To provide useful information on the choice of adequate drugs in the treatment of urinary tract infection (UTI) in spinal cord injury patients. MATERIALS ANDMETHODS:
The subjects were 34 spinal cord injured patients who were registered in Busan Spinal Cord Disabled Person Society and 111 patients with spinal cord injury who were admitted in 4 university hospitals in Busan between January 2004 and December 2005. We collected the patient's urine in July 2006 and performed comprehensive chart reviews of these patients. We studied the incidence of UTI, commonly cultured organisms, antimicrobial sensitivities, voiding methods and follow-up.RESULTS:
The incidence of UTI was 48.3% of 145 patients. The most common causative organism of UTI was Escherichia coli (27.1%), followed by Pseudomonas aeruginosa (22.9%) and Klebsiella pneumoniae (8.3%). Antimicrobial sensitivities of imipenem, amikacin and ceftazidime to Escherichia coli were respectively 100%, 92.3%, 80.8%. The sensitivities of Pseudomonas to the same agents were 63.6%, 31.8 %, 45.5% respectively. Ciprofloxacin showed decreased sensitivities of 38.5%, 31.8% respectively for Escherichia coli and Pseudomonas aeruginosa.CONCLUSION:
Our results implied decreasing susceptibility of ciprofloxacin, so it can be recommended to restrict the use of ciprofloxacin as a primary empirical antibiotic for UTI of spinal cord injured patients. Causative organisms of UTI are becoming more diverse. Also the incidence and antimicrobial sensitivities are changing as well. Therefore continuous observation with the appropriate treatment is needed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pseudomonas
/
Pseudomonas aeruginosa
/
Spinal Cord
/
Spinal Cord Injuries
/
Urinary Tract
/
Urinary Tract Infections
/
Amikacin
/
Ciprofloxacin
/
Ceftazidime
/
Imipenem
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2007
Type:
Article
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