A Study on the Adverse Events of the Yellow Fever Vaccine at an International Travelers' Clinic / 감염과화학요법
Infection and Chemotherapy
;
: 160-164, 2009.
Article
in English
| WPRIM
| ID: wpr-721619
ABSTRACT
BACKGROUND:
Yellow fever (YF) can be prevented through vaccination, but YF vaccination causes adverse events. The increasing number of travelers to YF-endemic areas prompted an investigation of YF vaccination's adverse events on Koreans. MATERIALS ANDMETHODS:
From January to December 2007, 318 live-17DD vaccinees at the International Travelers' Clinic of the National Medical Center were enrolled in this study.RESULTS:
The adverse events were evaluated through six telephone interviews of 309 subjects (male 168, 54.4%) on days 3, 6, 9, 16, 23, and 30 after the administration of the vaccine. There were 106 adverse events in 97 (31.4%) subjects aged 11 months to 70 years (male 56, 18.1%). Of the 34 (11.0%) subjects who had underlying diseases, 3 (1.0%) reported adverse events (P=0.06). Nineteen (6.1%) of the 72 (23.3%) subjects who concurrently received other vaccines also experienced adverse events (P=0.29). Those who had underlying illnesses and those aged 10 to 19 years reported more frequent adverse events (P=0.06 and 0.14, respectively), but the significance of this finding is uncertain. Most of the adverse events occurred within 10 days after the vaccination and spontaneously subsided.CONCLUSION:
This study shows that most of the YF vaccine's adverse events are well tolerated and that the vaccine safely protects a vaccinee from YF.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Yellow Fever
/
Vaccines
/
Interviews as Topic
/
Vaccination
/
Yellow Fever Vaccine
Type of study:
Qualitative research
Limits:
Aged
/
Humans
Language:
English
Journal:
Infection and Chemotherapy
Year:
2009
Type:
Article
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