Usage Analysis of Surgical Prophylaxis of Cephalosporins and Aminoglycosides in a University Hospital / 감염과화학요법
Infection and Chemotherapy
;
: 24-31, 2004.
Article
in Korean
| WPRIM
| ID: wpr-721925
ABSTRACT
BACKGROUND:
According to previous investigation on antibiotic use at Dankook University Hospital, cephalosporin and aminoglycoside were the most commonly used antibiotics accounting for 52.8% and 30.4% of total antibiotics used, respectively. In almost all cases, antibiotics were prescribed for prophylaxis rather than for treatment the ratio for prophylaxis vs. treatment intent was 3.91 and 3.6 1 for cephalosporin and aminoglycoside, respectively. Thus, we performed a study to investigate the current usage of cephalosporin and aminoglycoside before and after the surgical procedures.METHODS:
We retrospectively analyzed the appropriateness of prophylactic use of antibiotics on 14 major operative procedures (26.4% of total operations) for patients discharged during July, 1997.RESULTS:
Among 8 kinds of operative procedure performed on 105 cases, in which prophylactic antibiotic use was recommended, appropriate antibiotic use was observed in only 2 cases of non- perforating appendectomy. For 7 operative procedures, in which use of 1st generation cephalosporin is recommended, 1st cephalosporins were used only on 37.8% (44/92) of cases, whereas 2nd cephalosporins were used for most of other cases. An average of 2.5 DDD of 2nd cephalosporin, which was a pertinent dose, was used on non-perforating appendectomy. However, on all the other 7 operative procedures, the dose exceeded the recommended dose. Inappropriate antibiotic use was observed for 6 operative procedures, for which prophylactic antibiotic use was not recommended. The combination of cephalosporin and aminoglycoside was used in all but 3 types of operative procedures.CONCLUSION:
During most of the pre- and post-operative period, antibiotics were combined, overused, misused, and inappropriately used.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Appendectomy
/
Surgical Procedures, Operative
/
Cephalosporins
/
Retrospective Studies
/
Dichlorodiphenyldichloroethane
/
Aminoglycosides
/
Anti-Bacterial Agents
Type of study:
Observational study
Limits:
Humans
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2004
Type:
Article
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