Two Cases of Candida inconspicua Infection in Neutropenic Patients with Acute Leukemia / 감염과화학요법
Infection and Chemotherapy
;
: 164-168, 2006.
Article
in English
| WPRIM
| ID: wpr-721979
ABSTRACT
Non-albicans Candida species which are resistant to azole are emerging as important pathogens in patients with hematological malignancies who received antifungal prophylaxis. C. inconspicua is one of rare Candida spp. and resistant to fluconazole and deep infection due to C. inconspicua has not been reported in Korea so far. We reported here two cases of candidemia due to C. inconspicua in neutropenic patients with acute leukemia. C. inconspicua were presumed to be originated from gastrointestinal tract in both cases. The antifungal susceptibility test of C. inconspicua in case 1 showed resistance to fluconazole and itraconazole. Both cases were successfully treated by amphotericin B deoxycholate. Clinicians should keep in mind that non-albicans Candida species would be emerging pathogen in immunocompromised hosts and early recognition and appropriate use of antifungal agents is necessary.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Candida
/
Leukemia
/
Fluconazole
/
Amphotericin B
/
Immunocompromised Host
/
Fungemia
/
Itraconazole
/
Hematologic Neoplasms
/
Danazol
/
Gastrointestinal Tract
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Infection and Chemotherapy
Year:
2006
Type:
Article
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