In Vitro Susceptibility of piperacillin/tazobactam Against extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae / 감염과화학요법
Infection and Chemotherapy
;
: 49-51, 2008.
Article
in Korean
| WPRIM
| ID: wpr-722163
ABSTRACT
Minimal inhibitory concentrations (MIC) of piperacillin/tazobactam were determined on 20 clinical isolates of extended-spectrum beta-lactamase (ESBL)-producing E. coli and 30 isolates of ESBL- producing Klebsiella pneumoniae. MIC50 and MIC90 for ESBL-producing E. coli were 8/4 microg/ml and 256/4 microg/mL, respectively. MIC50 and MIC90 for ESBL-producing K. pneumoniae were 8/4 microg/mL and > 512/4 microg/mL, respectively. The susceptibilities of ESBL-producing E. coli and K. pneumoniae to piperacillin/tazobactam were 80% and 60%, respectively. Of 20 ESBL-producing E. coli strains, 11 (55%) were TEM-and CTX-M-positive, and SHV-negative. Of 30 ESBL-producing K. pneumoniae strains, ten (33%) were PCR positive for SHV and negative for TEM and CTX-M.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Beta-Lactamases
/
Polymerase Chain Reaction
/
Escherichia
/
Escherichia coli
/
Klebsiella
/
Klebsiella pneumoniae
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2008
Type:
Article
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