The Response of the Injured Articular Cartilage of Rabbit Knee after Injection of Autologous Blood
Journal of the Korean Academy of Rehabilitation Medicine
;
: 406-412, 2005.
Article
in Korean
| WPRIM
| ID: wpr-722437
ABSTRACT
OBJECTIVE:
To evaluate the effects of proliferant by injecting blood into the articular cartilage defect.METHOD:
The patella of rabbits were dislocated laterally and 2 mm circular and 2 mm depth full-thickness defect was made in the articular cartilage. We injected 0.2 cc autologous blood to the right defect and normal saline to the left one at 1 week after operation for six times with a 1 week interval. After injection for six weeks, the articular cartilage defect were obtained and stained with H-E and S-100.RESULTS:
The surface of the saline-injected group was easily distinguishable from the surrounding articular cartilage. But the blood-injected group had similar appearance to the surrounding cartilage, with the margin of the defect barely discerptible. Strong S-100 stained immune cartilage cells were observed in the blood-injected group.CONCLUSION:
The repairing process of the injured articular cartilage using autologous blood was shown to be much better than that of saline-injected group although the observation period was short and the number of animal was small. So we found that autologous blood effectively repaired osteochondral defects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Patella
/
Cartilage
/
Cartilage, Articular
/
Glucose
/
Knee
Limits:
Animals
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2005
Type:
Article
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