Influence of Lesion Location on Cortical Recovery Pattern in Hemiparetic Stroke Patients
Journal of the Korean Academy of Rehabilitation Medicine
;
: 412-417, 2004.
Article
in Korean
| WPRIM
| ID: wpr-722557
ABSTRACT
OBJECTIVE:
The aim of this study was to elucidate how the location of cerebral infarct influences cortical recovery pattern in hemiparetic stroke patients.METHOD:
Forty-three chronic stroke patients and 21 control subjects were recruited for the study. The patients were classified into 4 groups according to infarct locations cortex (CO), corona radiata (CR), posterior limb of the internal capsule (PL), and brainstem (BS). Functional MRI was performed using the blood oxygen level-dependent technique at 1.5 T with the motor task of hand grasp-release movements.RESULTS:
The activation pattern of the primary sensori-motor cortex (SM1) was found to be significantly influenced by the lesion locations, but that of the secondary motor area was not (Pearson's chi-square test, p<0.05). The contralateral' SM1 activation was the major response in the control group (85.7%) and in the BS group (75.0%). On the other hand, the major activation pattern was `peri-lesional' in the CO group (peri-lesional 57.1%, peri-lesional and ipsilateral 42.9%), `bilateral activation' in the CR (85.7%) and the PL group (100.0%).CONCLUSION:
Our results suggested that motor recovery mechanisms could be different according to location of cerebral infarct.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Brain Stem
/
Magnetic Resonance Imaging
/
Internal Capsule
/
Stroke
/
Extremities
/
Hand
/
Hemiplegia
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2004
Type:
Article
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