The Clinical Significance of Residual Latency in Diagnosis of Diabetic Neuropathy
Journal of the Korean Academy of Rehabilitation Medicine
;
: 1254-1262, 1998.
Article
in Korean
| WPRIM
| ID: wpr-722773
ABSTRACT
OBJECTIVE:
To determinate the reference values of residual latencies of motor nerves and to evaluate the early diagnostic value of residual latency.METHOD:
The subjects were 129 diabetes mellitus patients and 60 controls with no known neurological disorders. The patients were divided into two groups based on the conventional nerve conduction study Group 1, 75 patients without neuropathy; Group 2, 54 patients with neuropathy. The group 2 patients were subdivided into 4 sub- groups on the basis of conduction velocity and residual latency of the median nerve. Residual latencies were measured in all subjects and glycosylated hemoglobin percentages (HbA1c) were measured in the diabetes patients. In group 2, each nerve conduction parameter was correlated with the duration of diabetes and HbA1c. The duration of diabetes, HbA1c, and amplitude of median nerve response were compared between the subgroups of group 2 patients.RESULTS:
Motor residual latencies obtained from the controls were 1.93+/-0.28 msec, 1.53+/-0.24 msec, 2.46+/-0.43 msec, 2.21+/-0.53 msec in median, ulnar, deep peroneal and posterior tibial nerves, respectively. In group 1, motor residual latencies of median & deep peroneal nerves were significantly delayed compared with those of the controls. In group 2, motor residual latencies of median, ulnar, deep peroneal and posterior tibial nerves were significantly delayed more than those of the controls and group 1. In group 2, increased HbA1c correlated to the decreased conduction velocities of median, deep peroneal, posterior tibial nerves but not to the residual latencies. In the subgroup of group 2 (2-D), the nerve involved more distally showing lower compound muscle action potential and higher HbA1c.CONCLUSION:
Residual latency measurement can be a useful diagnostic method for the early detection of diabetic neuropathy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peroneal Nerve
/
Reference Values
/
Tibial Nerve
/
Action Potentials
/
Glycated Hemoglobin
/
Diabetes Mellitus
/
Diabetic Neuropathies
/
Diagnosis
/
Median Nerve
/
Nervous System Diseases
Type of study:
Diagnostic study
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
1998
Type:
Article
Similar
MEDLINE
...
LILACS
LIS