Evidence of Microstructural Abnormality on Descending Motor Pathway in Cerebral Plasied Children with Periventricular Leukomalacia: Diffusion Tensor MRI Study
Journal of the Korean Academy of Rehabilitation Medicine
;
: 340-343, 2003.
Article
in Korean
| WPRIM
| ID: wpr-722777
ABSTRACT
OBJECTIVE:
Using diffusion tensor MRI (DTI), to investigate the microstructural abnormality of corticospinal tract in the cerebral palsied children with periventricular leukomalacia on conventional MRI and to recognize the clinical usefulness of DTI.METHOD:
Seven patients were studied. DTI was peformed using 1.5T MR scanner (Vision Plus, Siemens, Erlangen, Germany) and fractional anisotropies of corona radiata, posterior limbs of internal capsules, and cerebral peduncles of midbrain in both hemisphere were calculated.RESULTS:
The fractional anisotropy was significantly decreased in all corona radiata, posterior limbs of internal capsules, cerebral peduncles of midbrain in six patients except one hemiplegic patient, compared with that of control group. In in the hemiplegic patient, the fractional anisotropy was reduced only in affected hemisphere. In addition, the fractional anisotropy tended to be also increased as gross motor function measure (GMFM) score was increased.CONCLUSION:
We believe that DTI may be efficient in evaluating microstructural abnormality on the motor pathway of brain and helpful in providing prognosis of clinical findings in cerebral palsied children with periventricular leukomalacia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Pyramidal Tracts
/
Leukomalacia, Periventricular
/
Brain
/
Mesencephalon
/
Tegmentum Mesencephali
/
Magnetic Resonance Imaging
/
Cerebral Palsy
/
Anisotropy
/
Internal Capsule
Type of study:
Prognostic study
Limits:
Child
/
Humans
/
Infant, Newborn
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS