The Resininferatoxin Therapy for the Hyperreflexive Neurogenic Bladder: Report of two cases of spinal cord injured patients
Journal of the Korean Academy of Rehabilitation Medicine
;
: 275-279, 2003.
Article
in Korean
| WPRIM
| ID: wpr-722786
ABSTRACT
Resiniferatoxin, a substance isolated from some species of Euphorbia, a cactus-like plant, shows pharmacological effects similar to those of capsaicin. We administered resiniferatoxin for treating detrusor hyperreflexia to patient with chronic spinal cord injury. Resiniferatoxin solution (100 ml at a concentration of 10-7, 10-6 M) was instilled twice into the bladder of patient with detrusor hyperreflexia and left in place for 30 minutes. Effects on bladder function were monitored at 1 month later follow-up. One month after the last resiniferatoxin instillation, patients reported a significant symptomatic improvement of their incontinence and increased mean bladder capacity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants
/
Spinal Cord
/
Spinal Cord Injuries
/
Urinary Bladder
/
Urinary Bladder, Neurogenic
/
Capsaicin
/
Reflex, Abnormal
/
Follow-Up Studies
/
Euphorbia
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2003
Type:
Article
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