A Case of Sebaceous Epithelioma / 대한피부과학회지

ABSTRACT

Sebaceous epithelioma is an uncommon and primary neoplasm of sebaceous gland. We report herein a case of sebaceous epithelioma in an 85-year-old female. Physical examination showed a solitary, 2.5 x 3.5cm sized, reddish. irregularly surfaced, and well defined tumor on the intercanthal area. Histopathological findings showed tumor parenchyma. romprised of several large nests of three kinds of epithelial cells, mature sebaceous cells, undifferentiated cells arranged in pa1isade fashion at the periphery of a cell nest, and transitional cells showing beginning fatty vacuolizatiorn of the cytoplasm. Electron micocopy revealed immature dark cells, transitional cells, and mature sebaceous cell which showed many scattered foci of sebaceous ditferentiation characterized by intracytoplasmic lipid droplets and glycogen particls.