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Effects of Growth Hormone Replacement Therapy on Quality of Life in Patients with Somatopause
Journal of the Korean Academy of Rehabilitation Medicine ; : 202-206, 2007.
Article in Korean | WPRIM | ID: wpr-723985
ABSTRACT

OBJECTIVE:

There is increasing interest in growth hormone (GH) replacement therapy to improve quality of life (QoL) of elderly with age-related decline in GH level (somatopause). The aim of this study was to evaluate the effect of GH replacement on the QoL in patients with somatopause.

METHOD:

A prospective study of 56 adults with somatopause was conducted. They were replaced with a GH over a 6-month period. QoL was assessed by using three self-rating questionnaires the Nottingham Health Profile (NHP), the Psychological General Well-Being Index (PGWBI) and theAssessment of Growth Hormone Deficiency in Adults (AGHDA).

RESULTS:

Significant impairment in QoL as measured by NHP, PGWBI and AGHDA were noted in patients with somatopause compared with age and sex matched normal population (p<0.05). There was significant improvement in QoL after 6-month of GH replacement (p<0.05).

CONCLUSION:

Six months GH replacement induced an improvement in the QoL of patients with somatopause.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality of Life / Growth Hormone / Prospective Studies / Surveys and Questionnaires Type of study: Observational study Limits: Adult / Aged / Humans Language: Korean Journal: Journal of the Korean Academy of Rehabilitation Medicine Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality of Life / Growth Hormone / Prospective Studies / Surveys and Questionnaires Type of study: Observational study Limits: Adult / Aged / Humans Language: Korean Journal: Journal of the Korean Academy of Rehabilitation Medicine Year: 2007 Type: Article