Teicoplanin-induced Elevation of Plasma Creatine Phosphokinase in the Patient with Wound Infection: A case report
Journal of the Korean Academy of Rehabilitation Medicine
;
: 469-471, 2008.
Article
in Korean
| WPRIM
| ID: wpr-724152
ABSTRACT
The use of teicoplanin is increasing with increase in the incidence of wound infections caused by methicillin-resistant Staphylococcus aureus. Teicoplanin has longer half-life than vancomycin, so it can be administerd once daily, whereas vancomycin has to be administered 3~4 times daily. Teicoplanin is known to have lesser side effect profiles than vancomycin, such as skin eruptions, ototoxicity and nephrotoxicity. A 27-year old women in vegetative state had a grade 3 pressure sore at coccyx area. We prescribe teicoplanin to manage wound infected by methicillin-resistant Staphylococcus aureus. Plasma creatine phosphokinase (CPK) was elevated abruptly at 9th day of teicoplanin therapy. Five days after discontinuation of teicoplanin, CPK was normalized. We experienced a case of elevation of plasma creatine phosphokinase associated with teicoplanin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Skin
/
Wound Infection
/
Vancomycin
/
Incidence
/
Teicoplanin
/
Coccyx
/
Persistent Vegetative State
/
Creatine
/
Creatine Kinase
Type of study:
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2008
Type:
Article
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