Effect of Prefrontal Repetitive Transcranial Magnetic Stimulationon the Enhancement of Working Memory
Journal of the Korean Academy of Rehabilitation Medicine
;
: 501-505, 2008.
Article
in Korean
| WPRIM
| ID: wpr-724667
ABSTRACT
OBJECTIVE:
To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) applied over the left prefrontal cortex on the enhancement of verbal working memory in healthy persons.METHOD:
High frequency (10 Hz) rTMS was applied over the left prefrontal cortex with the intensity of 100% resting motor threshold (RMT). A 3-back verbal working memory task was administered before, during (after applying 500 and 1,000 pulses, respectively), and 30 minutes after real or sham rTMS.RESULTS:
Real rTMS, compared with sham stimulation, significantly improved working memory performance. Accuracy of response increased significantly after applying 1,000 pulses of real rTMS (p<0.05). This effect maintained for 30 minutes after completion of stimulation (p<0.05). The error rate and reaction time did not change with rTMS. There was no noticeable side effect during or after rTMS.CONCLUSION:
1,000 pulses of 10 Hz rTMS administered to the left prefrontal cortex with the intensity of 100% RMT have positive impact on verbal working memory in healthy persons. Further study is necessary to address this effect of rTMS in patients with cognitive dysfunction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reaction Time
/
Salicylamides
/
Prefrontal Cortex
/
Transcranial Magnetic Stimulation
/
Magnets
/
Magnetics
/
Memory, Short-Term
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Academy of Rehabilitation Medicine
Year:
2008
Type:
Article
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