An Overview of Psychoneuroimmunology
Journal of the Korean Society of Biological Psychiatry
;
: 147-151, 2008.
Article
in Korean
| WPRIM
| ID: wpr-725130
ABSTRACT
This review briefly summarizes the relevant knowledge of psychoneuroimmunological basis for neuroimmunology, with particular emphasis on bidirectional neural-immune interactions. The immune system and the nervous system maintain extensive communication, including hardwiring of sympathetic and parasympathetic nerves to lymphoid organs. Immune system is modulated by various neurotransmitters such as acetylcholine, norepinephrine, substance P and histamine. Neuroendocrine hormones such as corticotrophin-releasing hormone(CRH) or substance P regulate cytokine balance. The immune system modulates brain activity including sleep and body temperature. Recent studies have revealed that psychological factors which influence immunity and immune-related disease may modulate brain-to -immune interaction. But, we still await the scientific research and evidences to prove whether or how behavioral or treatment intervention of stress can influence the development, progress or prevention of a specific disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Body Temperature
/
Brain
/
Psychoneuroimmunology
/
Acetylcholine
/
Histamine
/
Substance P
/
Norepinephrine
/
Neurotransmitter Agents
/
Immune System
/
Nervous System
Language:
Korean
Journal:
Journal of the Korean Society of Biological Psychiatry
Year:
2008
Type:
Article
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