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Current Update on Transcranial Direct Current Stimulation as Treatment for Major Depressive Disorder
Journal of the Korean Society of Biological Psychiatry ; : 89-100, 2018.
Article in Korean | WPRIM | ID: wpr-725220
ABSTRACT
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that delivers 1–2 mA of current to the scalp. Several clinical studies have been conducted to confirm the therapeutic effect of major depressive disorder (MDD) patients with tDCS. Some studies have shown tDCS's antidepressant effect, while the others showed conflicting results in antidepressant effects. Our aim of this review is to understand the biological bases of tDCS's antidepressant effect and review the results of studies on tDCS's antidepressant effect. For the review and search process of MDD treatment using tDCS, the US National Library of Medicine search engine PubMed was used. In this review, we discuss the biological mechanism of tDCS's antidepressant effect and the existing published literature including meta-analysis, systematic review, control trial, open studies, and case reports of antidepressant effects and cognitive function improvement in patients with MDD are reviewed. We also discuss the appropriate tDCS protocol for MDD patients, factors predictive of response to tDCS treatment, the disadvantages of tDCS in MDD treatment, and side effects.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Scalp / Brain / Cognition / Depressive Disorder, Major / Search Engine / Transcranial Direct Current Stimulation / Methods Type of study: Practice guideline / Prognostic study Limits: Humans Language: Korean Journal: Journal of the Korean Society of Biological Psychiatry Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Scalp / Brain / Cognition / Depressive Disorder, Major / Search Engine / Transcranial Direct Current Stimulation / Methods Type of study: Practice guideline / Prognostic study Limits: Humans Language: Korean Journal: Journal of the Korean Society of Biological Psychiatry Year: 2018 Type: Article