The Impacts of Alcohol Consumption on Glucose Metabolism / 임상당뇨병
Journal of Korean Diabetes
;
: 81-84, 2012.
Article
in Korean
| WPRIM
| ID: wpr-726810
ABSTRACT
The relationship between alcohol consumption and carbohydrate metabolism is complex and is not fully understood. Alcohol not only increases oxidative stress during metabolism, but also inhibits both gluconeogenesis and glycogenolysis in liver. Thus, acute alcohol intake can lead to hypoglycemia, particularly when glycogen stores are depleted or when alcohol is taken without meals. In addition, carbohydrate-rich food taken together with alcohol exaggerates insulin secretion and can cause reactive hypoglycemia about 2 to 3 hours after the meal. It is well established that mild to moderate alcohol consumption (3 drinks/day) is associated with reduced cardiovascular mortality through improvements in insulin sensitivity, lipid profiles, and blood pressure. These beneficial effects of alcohol may also be responsible for a decreased incidence of type 2 diabetes mellitus (T2DM) and a reduced risk of coronary heart disease (CHD) in patients with T2DM. However, excessive alcohol consumption causes higher insulin resistance and increases the risk of T2DM, and even reverses the favorable effects of moderate alcohol intake on CHD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Pressure
/
Alcohol Drinking
/
Insulin Resistance
/
Incidence
/
Oxidative Stress
/
Coronary Disease
/
Diabetes Mellitus
/
Diabetes Mellitus, Type 2
/
Alcohols
/
Carbohydrate Metabolism
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Diabetes
Year:
2012
Type:
Article
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