The Effects of Diabetes on Risk of Infection / 임상당뇨병
Journal of Korean Diabetes
;
: 14-19, 2017.
Article
in Korean
| WPRIM
| ID: wpr-726835
ABSTRACT
A relationship between diabetes and infection has long been accepted clinically. Host-specific factors that are thought to predispose diabetic patients to infection include hyperglycemia-related impairment of the immune response, vascular insufficiency, diabetic peripheral and autonomic neuropathy, and skin and mucosal colonization of pathogens. Some uncommon but life-threatening infections (e.g., malignant otitis media, rhinocerebral mucormycosis, gangrenous cholecystitis) occur almost exclusively in people with diabetes. Previous large population-based observational studies have reported strong associations between higher HbA1c and infection risks for both type 1 and type 2 diabetes. However, the potential of better long-term glycemic control to prevent infection remains controversial due to sparse randomized controlled trials. More high-quality, prospective studies with sufficient control of confounding factors and repeated HbA1c measures are necessary.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Otitis Media
/
Skin
/
Prospective Studies
/
Colon
/
Diabetes Mellitus
/
Hyperglycemia
/
Mucormycosis
Type of study:
Controlled clinical trial
/
Etiology study
/
Observational study
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Diabetes
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS