Bone and Energy Metabolism / 임상당뇨병
Journal of Korean Diabetes
;
: 174-177, 2013.
Article
in Korean
| WPRIM
| ID: wpr-726945
ABSTRACT
Bone remodeling requires a large amount of energy, and is regulated by various hormones. Leptin, produced by adipocytes, is a well-known regulator of energy balance and is also involved in controlling bone mass through interaction with the central nervous system. Serotonin, downstream of leptin, is also emerging as a candidate for controlling energy balance and bone metabolism. Currently, bone is also considered to be an endocrine regulator of energy metabolism. Osteocalcin, secreted from osteoblasts, is known to be a key regulator of glucose and fat metabolism. In this review, we describe a novel concept that asserts that there exists a biological link between bone and energy metabolism, and we summarize what is currently known about the relationship between bone and energy metabolism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoblasts
/
Serotonin
/
Osteocalcin
/
Central Nervous System
/
Bone Remodeling
/
Adipocytes
/
Neurotransmitter Agents
/
Leptin
/
Energy Metabolism
/
Glucose
Language:
Korean
Journal:
Journal of Korean Diabetes
Year:
2013
Type:
Article
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