Economical Sweating Function in Africans: Quantitative Sudomotor Axon Reflex Test
The Korean Journal of Physiology and Pharmacology
;
: 21-25, 2004.
Article
in English
| WPRIM
| ID: wpr-728507
ABSTRACT
People in tropics have the ability to tolerate heat by residential permanence in the tropics. Previously, we have shown that African and Thai subjects who lived for whole their lives in only their respective countries sweat less under hot conditions than South Koreans who also lived whole their lives in Korea. The difference in sweating responses was attributed to the dissimilar central and peripheral sweating mechanisms operating in people from both groups. In the present study, acetylcholine (ACh), the primary transmitter for the sudomotor functions, was iontophoretically administered to South Koreans and Africans to determine the characteristic sudorific responses of their acclimatized biologic make-up to their respective environments. Using quantitative sudomotor axon reflex test (QSART), direct (DIR) and axon reflex (AXR) responses were evaluated. The findings revealed that the sweat onset-time among South Koreans was 0.91 min earlier than among Africans (P< 0.01). The axon reflex sweat volume of nicotine receptor activity AXR (1) and sweat volume of muscarinic receptor activity DIR (2) among South Koreans were 79% and 53% greater (P< 0.01), respectively. These results indicate that the reduced thermal sweating among Africans is at least in part attributed to the diminished sensitivity of sweat glands to ACh.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reflex
/
Axons
/
Sweat
/
Sweat Glands
/
Sweating
/
Acetylcholine
/
Receptors, Muscarinic
/
Asian People
/
Hot Temperature
/
Acclimatization
Type of study:
Health economic evaluation
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
The Korean Journal of Physiology and Pharmacology
Year:
2004
Type:
Article
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