Epidemiological Comparison of viral hepatitis-hepatocellular carcinoma(HCC) and non viral hepatitis-hepatocellular carcinoma(HCC) / 한국역학회지
Korean Journal of Epidemiology
;
: 32-38, 2003.
Article
in Korean
| WPRIM
| ID: wpr-729137
ABSTRACT
BACKGROUND:
Korea is one of high incidence areas of Hepatocellular carcinoma (HCC) and major etiologic factor is hepatitis B virus (HBV). In future incidence of HBV related HCC may decrease and non viral hepatitis HCC (Non-B,C HCC) relatively increase because of widely used vaccination for HBV. To evaluate epidemiological characters of Non-B,C HCC, We divided HCC by viral or non-viral feature and compared each others.METHODS:
185 patients firstly diagnosed HCC and 455 normal subjects included from January 1997 to December 2000 and divided into 3 groups, HBV group (positive HBsAg), HCV group (positive anti-HCV Ab) and Non-B,C group (both negative HBsAg and anti-HCV Ab).RESULTS:
136 cases were HBV group (73.5%), 19 cases were HCV group (10.3%) and 27 cases were Non-B,C group (14.6%). Mean age of Non-B,C group at diagnosis was higher than HBV group (64.1+/-7.1 vs 55.6+/-7.7). Non-B,C HCC were more associated with alcohol abuse and rural residence (p<0.01). There was no difference of family history of liver disease, coexistence rate of liver cirrhosis and occupation.CONCLUSION:
Non-B,C HCC tended to be older in mean age than HBV HCC and more associated with alcohol abuse and rural residence. This characteristics of Non-B,C HCC supposed to be from difference in alcohol consumption and environment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Alcohol Drinking
/
Fibrinogen
/
Hepatitis B virus
/
Incidence
/
Vaccination
/
Carcinoma, Hepatocellular
/
Diagnosis
/
Alcoholism
/
Hepatitis
/
Hepatitis B Surface Antigens
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Epidemiology
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS