Cytotoxicity of Paecilomyces tenuipes Against Human Carcinoma Cells, HepG2 and MCF-7 In Vitro
Mycobiology
; : 170-172, 2001.
Article
in En
| WPRIM
| ID: wpr-729286
Responsible library:
WPRO
ABSTRACT
The methanolic extract of fruiting body of Paecilomyces tenuipes DGUM 32001 showed significant cytotoxicity against human cancer cells: HepG2 and MCF-7. The methanolic extract was further fractionated with organic solvents such as chloroform and ethyl acetate in that order. Among the fractions tested, the ethyl acetate fraction showed the highest cytotoxicity against the carcinoma tested. The IC50 values of ethyl acetate fraction against HepG and MCF-7 were 40 and 9.6 microg/ml, respectively.
Key words
Full text:
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Index:
WPRIM
Main subject:
Solvents
/
Paecilomyces
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Chloroform
/
Inhibitory Concentration 50
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Methanol
/
Hep G2 Cells
/
Fruit
Limits:
Humans
Language:
En
Journal:
Mycobiology
Year:
2001
Type:
Article