Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus
Mycobiology
;
: 230-235, 2006.
Article
in English
| WPRIM
| ID: wpr-729373
ABSTRACT
Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Water
/
Chromatography, Gel
/
Immunization
/
Aspartic Acid
/
Alanine
/
Absorption
/
Alkalies
/
Fruit
/
Molecular Weight
Language:
English
Journal:
Mycobiology
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS