Mechanism of TUDCA for retinitis pigmentosa / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1403-1406, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-731244
ABSTRACT
@#Tauroursodeoxycholic acid(TUDCA)is formed by taurine conjugated of ursodeoxycholic acid(UDCA). It has the role of neurotrophic factor in anti-inflammatory, anti-apoptosis and reducing the activation of microglial cells. These effects may be one of the most critical of all pathological stages of retinitis pigmentosa. Preclinical trials have shown that TUDCA had potential therapeutic value for retinal degeneration disease. This article discusses how TUDCA can slow down the process of retinal degeneration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2018
Type:
Article
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