Detecting the Expression of ST3GalⅤ in Human Hepatic Carcinoma Cell Lines by Sialyltransferase DNA Microarray / 沈阳医学院学报
Journal of Shenyang Medical College
;
(6): 142-145, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-731750
ABSTRACT
Objective:
To investigate the differential expression of ST3GalⅤ in human hepatic carcinoma cell lines, HepG?2 and SMMC?7721 and normal hepatic cell line, L?02 by sialyltransferase DNA microarray.Methods:
Expression of ST3Gal family was measured with DNA microarray. Western blot was used to verify DNA microarrays data.Result:
ST3GalⅤ downregulated in HepG?2 and SMMC?7721 cell lines, compared with control cell line.Conclusion:
The downregulation of ST3GalⅤ in HepG?2 and SMMC?7721 cell lines may result in the reduction of GD1a and influence the hepatocyte proliferations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Shenyang Medical College
Year:
2016
Type:
Article
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