Probable etiology of mild encephalopathy with reversible isolated lesions in the corpus callosum in children: A review of 20 cases from northern China
Neurology Asia
;
: 153-158, 2018.
Article
in English
| WPRIM
| ID: wpr-732548
ABSTRACT
Objective:
To explore the etiological spectrum of solitary corpus callosum lesions in children.Methods:
Retrospective analysis ofclinical features, laboratory findings and brain MRI of 20 children with isolated corpus callosum lesions and treated in Taiyuan, northern China.Results:
The average age of onset was 3.64±3.25 years old. The main clinical symptoms were seizures (13 cases, 65%), fever (10 cases, 50%), gastrointestinal symptoms with vomiting or diarrhea (10 cases, 50%), neck stiffness (5 cases, 25%), altered states of consciousness (4 cases, 20%). Brain MRI showed the splenium lesion to be oval in shape. Repeat MRI showed reversal of the lesion after a mean of 29.5 days. Though the patients were suspected to have probable viral encephalitis, no etiology was found in 15 cases. There was associated gastroenteritis in 5 patients, and rotavirus confirmed in stool in 4 patients. Close to half the patients had hyponatremia. None of the patient had had persistent neurobehavioural symptoms on follow-up at 12-14 months.Conclusions:
This study from northern China confirmed that isolated solitary corpus callosum lesion is benign
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
English
Journal:
Neurology Asia
Year:
2018
Type:
Article
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