Air pollution and childhood asthma / 国际儿科学杂志

ABSTRACT

Air pollution plays an important role in the occurrence and development of childhood asthma and is one of the risk factors of asthma.In daily life,there are a great variety of air pollutants.They have a wide range of sources.They can increase the risk of asthma onset and acute exacerbations,impair the lung function of children,lead to immunologic derangement,enhance allergenicity and reduce the responsiveness to treatment via various mechanisms and signal pathways.Age,gender,obesity,sensitization,antioxidants supplement,protective measures and other factors impose the adverse effects of pollutants on the children.Although some progress has been made in the research of air pollution and asthma in children,many problems are still needed to be further explored.This review summarizes the common air pollutants on the initiation and evolution of childhood asthma.